DNA methods

Northern Blotting

Sometimes it's a bit hard to understand, but there is humor in science. In the 1970s, E.M. Southern developed a method for locating a particular sequence of DNA within a complex mixture. This technique came to be known as Southern blotting. In a tongue-in-cheek fashion, those who used a similar method for locating a sequence of RNA named it Northern blotting. It is also known as Northern hybridization, or RNA hybridization.

The procedure for and theory behind Northern blotting is almost identical to that of Southern blotting, except you are working with RNA instead of DNA. Please see the section on Southern blotting for more information.

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Bibliographic details:

  • Article: Northern Blotting
  • Author(s): Guruatma "Ji" Khalsa
  • Publisher: Arizona State University School of Life Sciences Ask A Biologist
  • Site name: ASU - Ask A Biologist
  • Date published: April 12, 2010
  • Date accessed: October 2, 2023
  • Link: https://askabiologist.asu.edu/northern-blotting

APA Style

Guruatma "Ji" Khalsa. (2010, April 12). Northern Blotting. ASU - Ask A Biologist. Retrieved October 2, 2023 from https://askabiologist.asu.edu/northern-blotting

American Psychological Association. For more info, see http://owl.english.purdue.edu/owl/resource/560/10/

Chicago Manual of Style

Guruatma "Ji" Khalsa. "Northern Blotting". ASU - Ask A Biologist. 12 April, 2010. https://askabiologist.asu.edu/northern-blotting

MLA 2017 Style

Guruatma "Ji" Khalsa. "Northern Blotting". ASU - Ask A Biologist. 12 Apr 2010. ASU - Ask A Biologist, Web. 2 Oct 2023. https://askabiologist.asu.edu/northern-blotting

Modern Language Association, 7th Ed. For more info, see http://owl.english.purdue.edu/owl/resource/747/08/
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