DNA (deoxyribonucleic acid): molecular instructions that guide how all living things develop and function...more
Egg: a female gamete, which keeps all the parts of a cell after fusing with a sperm.
Gamete: specialized cells found in your reproductive organs that have half the amount of DNA of somatic cells. These cells combine to make a fertilized egg... more
Gene: a region of DNA that instructs the cell on how to build protein(s). As a human, you usually get a set of instructions from your mom and another set from your dad... more
Nucleus: where DNA stays in the cell, plural is nuclei.
Sperm: a male gamete, which fuses with the egg during fertilization... more
Scientists found that they could make clones through a process called nuclear transfer. Nuclear transfer uses the technology that puts a sperm into an egg for artificial fertilization, but takes it a step further.
Almost all cells have a nucleus. A nucleus is where the DNA or genetic blueprint for life is located inside the cell. When you remove the nucleus, it is called enucleation. Pronounced: E' - new - klee - a - shun. Removing the nucleus requires the use of a small needle that is inserted into the cell. The needle sucks the nucleus out of the cell. The same process is performed on another cell. The nuclei can be switched then. The cells recover from the needle wound and start working again.
Credits: Image from Mizutani, E. et al. Generation of cloned mice and nuclear transfer embryonic stem cell lines from urine-derived cells. Sci. Rep. 6, 23808; doi: 10.1038/srep23808 (2016). Retrieved July 2, 2016 from https://www.nature.com/articles/srep23808 Published under Creative Commons BY 4.0 International.
Faye Farmer. (2009, September 29). Nuclear Transfers. ASU - Ask A Biologist. Retrieved December 6, 2022 from https://askabiologist.asu.edu/content/nuclear-transfers
Faye Farmer. "Nuclear Transfers". ASU - Ask A Biologist. 29 September, 2009. https://askabiologist.asu.edu/content/nuclear-transfers
Faye Farmer. "Nuclear Transfers". ASU - Ask A Biologist. 29 Sep 2009. ASU - Ask A Biologist, Web. 6 Dec 2022. https://askabiologist.asu.edu/content/nuclear-transfers
Pipette holding egg (left) while nucleus is removed from the cell using a fine needle (right).