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DNA: deoxyribonucleic acid is the information "blue-print" of the cell. It is a nucleic acid and is made from building blocks called nucleotides. This genetic information is passed from parent to child... more
Egg: a female gamete, which keeps all the parts of a cell after fusing with a sperm.
Gamete: specialized cells found in your reproductive organs that have half the amount of DNA of somatic cells. These cells combine to make a fertilized egg... more
Scientists found that they could make clones through a process called nuclear transfer. Nuclear transfer uses the technology that puts a sperm into an egg for artificial fertilization, but takes it a step further.
Almost all cells have a nucleus. A nucleus is where the DNA or genetic blueprint for life is located inside the cell. When you remove the nucleus, it is called enucleation. Pronounced: E' - new - klee - a - shun. Removing the nucleus requires the use of a small needle that is inserted into the cell. The needle sucks the nucleus out of the cell. The same process is performed on another cell. The nuclei can be switched then. The cells recover from the needle wound and start working again.
Credits: Image from Mizutani, E. et al. Generation of cloned mice and nuclear transfer embryonic stem cell lines from urine-derived cells.Sci. Rep. 6, 23808; doi: 10.1038/srep23808 (2016). Retrieved July 2, 2016 from http://www.nature.com/articles/srep23808. Published under Creative Commons BY 4.0 International.
Dr. Biology. (2009, September 29). Nuclear Transfers. ASU - Ask A Biologist. Retrieved August 16, 2018 from https://askabiologist.asu.edu/content/nuclear-transfers
Dr. Biology. "Nuclear Transfers". ASU - Ask A Biologist. 29 September, 2009. https://askabiologist.asu.edu/content/nuclear-transfers
Dr. Biology. "Nuclear Transfers". ASU - Ask A Biologist. 29 Sep 2009. ASU - Ask A Biologist, Web. 16 Aug 2018. https://askabiologist.asu.edu/content/nuclear-transfers
Pipette holding egg (left) while nucleus is removed from the cell using a fine needle (right).